15 Oct XEVONTA
Innovation in membrane technology
Housing & membrane modifications with effects on performance:
• Bundle head expansion
• Optimum packing density with adapted housing diameter
• Microtexture
Support homogeneous dialysis fluid distribution in the dialyzer and leads to highest diffusive clearance.
Innovation in membrane technology
Optimal wall thickness / internal diameter ratio for high convective clearance
The reduction of the inner diameter… …leads to an increased pressure drop through the length of the dialyzer. Result: higher internal filtration and middle molecule removal
Nano membrane technology
amembris
high-performance, biocompatible polysulfone-based membrane
membrane with nano structure
• Precisely defined pore diameters
• Maximized number of pores
• Narrow pore size distribution
Highest permeability
Optimal selectivity
Challenge the thinking
Clinical studies on HDF
Today the focus of HDF is the elimination of toxins:
• Mortality
• Determination of clearance of uremic toxins
• Determination of serum albumin in blood
• Influence of substitution volume
• Others
Challenge the thinking
Increasing the convective volume during HDF is associated with significant protein loss, mainly albumin.
Challenge the thinking
Albumin removal in g / HDF session
Intelligence in HDF
Achieving the balance between elimination and retention.